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. 1993 Jun;55(6):1418-21.

Xenotransplantation: baboons as potential liver donors? Scientific and ethical issues

L Chiche  1 , R Adam, S Caillat-Zucman, D Castaing, J F Bach, H Bismuth
Affiliations
  • PMID: 8516828

Xenotransplantation: baboons as potential liver donors? Scientific and ethical issues

L Chiche et al. Transplantation. 1993 Jun.

Abstract

The dramatic development of liver transplantation compared to a relative shortage of donors has brought a renewed interest to xenotransplantation. Because of anatomical and immunological compatibilities, nonhuman primates are the most appropriate donors. The aim of this work was to analyze the different problems of a baboon-to-man liver xenotransplantation. Thirty baboons bred in a French Primatology Center were studied. The analysis of anatomical, microbiological, and immunological data showed that only 8 baboons out of 30 were suitable as donors for xenotransplantation. Considering these data and the ethical issues, the actual feasibility of xenotransplantation programs is discussed.

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