Radiological presentations of Castleman's disease

Abstract

The radiographic appearances of three cases of Castleman's disease of hyaline vascular type are reported. CT demonstrated homogeneous masses with marked contrast enhancement. Calcification was seen in one, and associated lymphadenopathy was seen in two. All tumors were hypervascular with prominent tumor blush on angiography. Sonography showed the masses to be hypoechoic with hyperechoic spots. On MR imaging, all tumors had homogeneous architecture with hypointensity on T1-weighted images and hyperintensity on T2-weighted images. In tumors with above characteristics in areas where lymphoid tissue is normally found, Castleman's disease should be added to the list of differential diagnosis.