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. 1995 Jun;19(6):319-24.
doi: 10.1007/BF00052389.

Artificial immunization of rabbits with Hyalomma dromedarii tick-derived midgut antigen

R Kumar  1 , R Kumar
Affiliations

Artificial immunization of rabbits with Hyalomma dromedarii tick-derived midgut antigen

R Kumar et al. Exp Appl Acarol. 1995 Jun.

Abstract

New Zealand white rabbits were immunized with partly fed Hyalomma dromedarii tick-derived midgut concealed antigens (supernate and pellet fractions) and Freund's complete adjuvant (FCA). The rabbits received three inoculations subcutaneously on days 0, 14 and 21 at a dose rate of 1 mg antigen per animal. The effects of the immunity induced was determined by infesting the rabbits with adult H. dromedarii ticks. In immunized rabbits a significant reduction in tick yield, engorgement weight, oviposition period, egg mass weight and percentage of egg hatchability was found. The gut supernatant antigen fraction induced the best protection in terms of reduced feeding and reproductive performance of the ticks.

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