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Case Reports
. 1995 Dec;59(3):427-9.
doi: 10.1006/gyno.1995.9948.

Malignant degeneration of a mature cystic teratoma five decades after discovery

D Griffiths  1 , J Wass, K Look, G Sutton
Affiliations
Case Reports

Malignant degeneration of a mature cystic teratoma five decades after discovery

D Griffiths et al. Gynecol Oncol. 1995 Dec.

Abstract

Malignant degeneration of mature cystic teratomas has been reported in 1-3% of cases. A patient with the unusual occurrence of a stage IIIC squamous cell carcinoma arising in a mature teratoma over 50 years after initial diagnosis is presented. The patient was treated with pelvic radiotherapy. The role of serum squamous cell carcinoma antigen in detecting degeneration of mature cystic teratomas at an early stage is considered.

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