Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1995 Nov;61(11):3977-80.
doi: 10.1128/aem.61.11.3977-3980.1995.

Direct sequencing of hepatitis A virus strains isolated during an epidemic in France

V Apaire-Marchais  1 , B H Robertson, V Aubineau-Ferre, M G Le Roux, F Leveque, L Schwartzbrod, S Billaudel
Affiliations

Direct sequencing of hepatitis A virus strains isolated during an epidemic in France

V Apaire-Marchais et al. Appl Environ Microbiol. 1995 Nov.

Abstract

Direct sequencing of PCR products was used to study the VP1 region of the hepatitis A virus (HAV) genome (position 2199 to 2356) of nine strains isolated from human stools collected during a hepatitis A epidemic (western France, 1992), three strains from environmental samples (1990, 1991, and 1992), and two HAV cell culture isolates (the French strain CF53/Lyon and strain CLF). These viruses differed from CF53/Lyon (genotype I) by between 1 and 10.3%, and results indicated the existence of two groups of strains belonging to two different subgenotypes (IA and IB). With this sequencing technique it was possible to monitor the epidemiology of HAV and study its relations.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Proc Natl Acad Sci U S A. 1985 May;82(9):2627-31 - PubMed
    1. J Virol. 1987 Jan;61(1):50-9 - PubMed
    1. Virus Res. 1987 Aug;8(2):153-71 - PubMed
    1. Virus Res. 1989 Jul;13(3):207-12 - PubMed
    1. Mol Cell Probes. 1994 Apr;8(2):117-24 - PubMed

MeSH terms