[Serum digoxin levels in the pediatric age (author's transl)]

Abstract

Serum digoxin levels during maintenance therapy in children of four different age groups were determined by a radioimmunoassay technique. For each patient, three determinations, at the peak level, at the plateau and at the final phase, were done. The newborn group showed in all three phases serum digoxin levels significantly higher than those found in the other groups, in spite of an only slightly higher dosage of digoxin used in comparison to the other groups.