Hyaluronidases--a group of neglected enzymes
- PMID: 8528065
- PMCID: PMC2143229
- DOI: 10.1002/pro.5560040902
Hyaluronidases--a group of neglected enzymes
Abstract
Hyaluronan is an important constituent of the extracellular matrix. This polysaccharide can be hydrolyzed by various hyaluronidases that are widely distributed in nature. The structure of some bacterial and animal enzymes of this type has recently been elucidated. It could be shown that the hyaluronidases from bee and hornet venom and the PH-20 hyaluronidase present on mammalian spermatozoa are homologous proteins.
Similar articles
-
Hyaluronidases in tissue invasion.Invasion Metastasis. 1997;17(6):297-311. Invasion Metastasis. 1997. PMID: 9949289 Review.
-
The magic glue hyaluronan and its eraser hyaluronidase: a biological overview.Life Sci. 2007 May 1;80(21):1921-43. doi: 10.1016/j.lfs.2007.02.037. Epub 2007 Mar 6. Life Sci. 2007. PMID: 17408700 Review.
-
Sulphated oligosaccharides as inhibitors of hyaluronidases from bovine testis, bee venom and Streptococcus agalactiae.Planta Med. 2005 Aug;71(8):727-32. doi: 10.1055/s-2005-871255. Planta Med. 2005. PMID: 16142636
-
Chondroprotective action of chondroitin sulfate. Competitive action of chondroitin sulfate on the digestion of hyaluronan by bovine testicular hyaluronidase.Int J Tissue React. 1991;13(6):311-7. Int J Tissue React. 1991. PMID: 1818045
-
Effect of depletion of interstitial hyaluronan on hydraulic conductance in rabbit knee synovium.J Physiol. 1998 Jun 15;509 ( Pt 3)(Pt 3):695-710. doi: 10.1111/j.1469-7793.1998.695bm.x. J Physiol. 1998. PMID: 9596792 Free PMC article.
Cited by
-
Two novel functions of hyaluronidase-2 (Hyal2) are formation of the glycocalyx and control of CD44-ERM interactions.J Biol Chem. 2009 Nov 27;284(48):33495-508. doi: 10.1074/jbc.M109.044362. Epub 2009 Sep 25. J Biol Chem. 2009. PMID: 19783662 Free PMC article.
-
CS lyases: structure, activity, and applications in analysis and the treatment of diseases.Adv Pharmacol. 2006;53:187-215. doi: 10.1016/S1054-3589(05)53009-6. Adv Pharmacol. 2006. PMID: 17239767 Free PMC article. Review. No abstract available.
-
Recruitment of glycosyl hydrolase proteins in a cone snail venomous arsenal: further insights into biomolecular features of Conus venoms.Mar Drugs. 2012 Feb;10(2):258-280. doi: 10.3390/md10020258. Epub 2012 Jan 31. Mar Drugs. 2012. PMID: 22412800 Free PMC article.
-
Pharmacological characterization of venoms from three theraphosid spiders: Poecilotheria regalis, Ceratogyrus darlingi and Brachypelma epicureanum.J Venom Anim Toxins Incl Trop Dis. 2015 Jun 17;21:15. doi: 10.1186/s40409-015-0017-8. eCollection 2015. J Venom Anim Toxins Incl Trop Dis. 2015. PMID: 26085827 Free PMC article.
-
Clinical Applications of Hyaluronidase.Adv Exp Med Biol. 2019;1148:255-277. doi: 10.1007/978-981-13-7709-9_12. Adv Exp Med Biol. 2019. PMID: 31482503 Review.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources