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Review
. 1995 Aug;3(8):327-30.
doi: 10.1016/s0966-842x(00)88965-9.

The search for virulence determinants in Aspergillus fumigatus

J P Bouchara  1 , G Tronchin, G Larcher, D Chabasse
Affiliations
Review

The search for virulence determinants in Aspergillus fumigatus

J P Bouchara et al. Trends Microbiol. 1995 Aug.

Abstract

The development of aspergillosis in an immunodeficient host depends on interactions between fungal and host components. The recognition by Aspergillus fumigatus of fibrinogen and laminin, and the secretion of extracellular proteinases and ribonucleotoxin have been suggested to mediate adherence to mucosal surfaces and subsequently to bring about host-tissue invasion.

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