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. 1995 Sep 1;29(1):225-8.
doi: 10.1006/geno.1995.1235.

Distribution of the mammalian Stat gene family in mouse chromosomes

N G Copeland  1 , D J Gilbert, C Schindler, Z Zhong, Z Wen, J E Darnell Jr, A L Mui, A Miyajima, F W Quelle, J N Ihle, et al.
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Free article

Distribution of the mammalian Stat gene family in mouse chromosomes

N G Copeland et al. Genomics. .
Free article

Abstract

Studies of transcriptional activation by interferons and a variety of cytokines have led to the identification of a family of proteins that serve as signal transducers and activators of transcription, Stats. Here, we report that the seven mouse Stat loci map in three clusters, with each cluster located on a different mouse autosome. The data suggest that the family has arisen via a tandem duplication of the ancestral locus, followed by dispersion of the linked loci to different mouse chromosomes.

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