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Comparative Study
. 1995 Sep 1;29(1):285-7.
doi: 10.1006/geno.1995.1247.

Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases

J A Hejna  1 , H Saito, L S Merkens, T V Tittle, P M Jakobs, M A Whitney, M Grompe, A S Friedberg, R E Moses
Affiliations
Comparative Study

Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases

J A Hejna et al. Genomics. .

Abstract

We have cloned a novel human cDNA, INPPL1 (GenBank Accession No. L36818), which maps to 11q23. The corresponding mRNA is 4657 nt in length and is widely expressed in both fetal and adult tissues. An open reading frame of 3441 nt encodes a putative polypeptide that shares several domains with inositol triphosphate phosphatases. Several polymorphisms have been mapped to the 3'-untranslated region, yet the putative coding region showed no polymorphisms in nine independent cDNA samples.

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