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. 1995 Aug;59(4):293-307.
doi: 10.1016/0001-706x(95)00094-u.

Putative Leishmania hybrids in the Eastern Andean valley of Huanuco, Peru

J C Dujardin  1 , A L Bañuls, A Llanos-Cuentas, E Alvarez, S DeDoncker, D Jacquet, D Le Ray, J Arevalo, M Tibayrenc
Affiliations

Putative Leishmania hybrids in the Eastern Andean valley of Huanuco, Peru

J C Dujardin et al. Acta Trop. 1995 Aug.

Abstract

During an outbreak of tegumentary leishmaniasis that developed in the 1990s in the Eastern Andean valley of Huanuco, Peru, the coexistence of Andean (uta) and sylvatic leishmaniases was suspected for ecological and geographical reasons, and sympatric sampling was carried out. Seven human isolates of Leishmania were characterized by multilocus enzyme electrophoresis, random amplification of polymorphic DNA and molecular karyotyping. The three methods identified 3 isolates as L. braziliensis, and 4 isolates as putative hybrids with characters of L. braziliensis and L. peruviana. Data from Huanuco are compared to previous results from other areas endemic for uta. Biological and epidemiological implications are discussed.

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