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. 1996 Jan;173(1):245-8.
doi: 10.1093/infdis/173.1.245.

A community-based study of human immunodeficiency virus type 2 provirus load in rural village in West Africa

K Ariyoshi  1 , N Berry, A Wilkins, D Ricard, P Aaby, A Nauclér, P T Ngom, O Jobe, S Jaffar, F Dias, R S Tedder, H Whittle
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A community-based study of human immunodeficiency virus type 2 provirus load in rural village in West Africa

K Ariyoshi et al. J Infect Dis. 1996 Jan.

Abstract

A community-based study of provirus load in human immunodeficiency virus (HIV) type 2-infected subjects was done in a rural village in Guinea-Bissau. HIV-2 provirus load varied considerably, with a geometric mean of 124.3 (95% confidence interval, 86.0-179.6) copies/10(5) CD4 cells, which is a level similar to that found in HIV-1 infection. Neither malaria parasitemia, active syphilis, or human T cell leukemia virus coinfection significantly influenced provirus load, nor did age. Eleven of 104 HIV-2-infected subjects had died after 3 years of follow-up; 9 of those who died had a high provirus load of > or = 100 copies/10(5) CD4 cells and a relatively low CD4 cell percentage of < 29%.

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