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Review
. 1996 Jan 12;271(5246):173-8.
doi: 10.1126/science.271.5246.173.

Immunology taught by viruses

R M Zinkernagel  1
Affiliations
Review

Immunology taught by viruses

R M Zinkernagel. Science. .

Abstract

The survival of viruses depends on the survival of susceptible hosts. The vertebrate immune system and viruses have therefore coevolved complementary facets. Evidence from various balanced virus-host relationships illustrates that immunological specificity and memory may best be defined biologically and that the mature immune system does not discriminate between "self" and "nonself." Rather, B cells distinguish antigen patterns, whereas T cell responses depend on localization, transport, and kinetics of antigen within lymphatic organs.

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  • Immunology taught by Darwin.
    McKean KA, Nunney L, Zuk M. McKean KA, et al. Science. 1996 May 3;272(5262):634-5. doi: 10.1126/science.272.5262.634. Science. 1996. PMID: 8614814 No abstract available.

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