The effect of tympanic membrane perforation size on umbo velocity in the rat
- PMID: 8544632
- DOI: 10.1097/00005537-199601000-00014
The effect of tympanic membrane perforation size on umbo velocity in the rat
Abstract
The tympanic membrane (TM) in adult rats was surgically exposed and laser interferometry was used to measure TM velocity at the umbo for frequencies between 1.0 and 40.0 kHz. Velocity measures were obtained for five conditions: TM intact, and four progressively larger holes cut into the posterior region of the membrane. Photomicrographs of each condition were used to calculate the percentage of pars tensa lost to the perforation. The relation between TM velocity and stimulus sound pressure level (SPL) was also examined for each of the conditions. The results revealed a systematic loss in low-frequency velocity as perforation size increased. These observations were consistent with clinical reports of low-frequency hearing loss in the perforated human TM. The rat appears to be a successful model for studying this form of conductive pathology.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous