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. 1995 Oct;91(2):362-6.
doi: 10.1111/j.1365-2141.1995.tb05304.x.

The expression of mRNA for fibrinogen in megakaryocytes isolated from patients with T-cell lymphoma

M Podolak-Dawidziak  1 , V Hancock, R Lelchuk, S Kotlarek-Haus, J F Martin
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The expression of mRNA for fibrinogen in megakaryocytes isolated from patients with T-cell lymphoma

M Podolak-Dawidziak et al. Br J Haematol. 1995 Oct.

Abstract

The expression of fibrinogen mRNA was studied by in situ hybridization in freshly isolated megakaryocytes in 14 newly-diagnosed patients: seven with non-Hodgkin's lymphoma (NHL), three with immune thrombocytopenic purpura (ITP) and four haematologically normal patients prior to coronary artery bypass surgery. Fibrinogen mRNA in megakaryocytes was not detected in ITP, B-cell lymphomas or in healthy donors. However, it was present in all patients with the high-grade T-cell lymphomas, both with and without thrombocytopenia.

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