Surgical vs. clinical staging of endometrial carcinoma. The impact on treatment modification, morbidity and survival
- PMID: 8549600
Surgical vs. clinical staging of endometrial carcinoma. The impact on treatment modification, morbidity and survival
Abstract
Objective: To assess the impact of surgical staging on treatment modification and outcome in endometrial carcinoma (EC) patients.
Methods: Two groups of histologically confirmed clinical Stage I and II EC patients, diagnosed during two time periods (1976-1984 and 1985-1991), were retrospectively compared. Sixty-five patients diagnosed during the first period were staged only clinically and treated according to a protocol based on this staging system. Fifty-six patients diagnosed during the second period were staged surgically and treatment was modified according to surgical pathological findings.
Results: The findings based on the surgical staging spared radiotherapy in some patients and prompted additional treatment in others. The morbidity and survival were similar in the two groups.
Conclusions: Surgical pathological findings in EC patients may modify management and contribute to prognostic significance. No effect on postoperative morbidity or on actuarial survival was demonstrated.