Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Jan;178(1):280-3.
doi: 10.1128/jb.178.1.280-283.1996.

Frur mediates catabolite activation of pyruvate kinase (pykF) gene expression in Escherichia coli

S A Bledig  1 , T M Ramseier, M H Saier Jr
Affiliations

Frur mediates catabolite activation of pyruvate kinase (pykF) gene expression in Escherichia coli

S A Bledig et al. J Bacteriol. 1996 Jan.

Abstract

Expression of a pykF-lacZ fusion was studied as a function of the carbon source in wild-type strains and strains lacking or overproducing the FruR protein of Escherichia coli. FruR controls the response to the carbon source by repressing pykF expression more strongly under gluconeogenic than under glycolytic conditions, a phenomenon we term catabolite activation.

PubMed Disclaimer

References

    1. J Biol Chem. 1971 Nov;246(21):6511-21 - PubMed
    1. J Gen Microbiol. 1972 Jun;71(1):181-90 - PubMed
    1. Bacteriol Rev. 1972 Dec;36(4):525-57 - PubMed
    1. Mol Gen Genet. 1983;192(1-2):293-4 - PubMed
    1. Mol Gen Genet. 1986 Jun;203(3):435-44 - PubMed

Publication types

MeSH terms

LinkOut - more resources