Bromocriptine is ineffective in the treatment of chronic nonfluent aphasia
- PMID: 8553797
Bromocriptine is ineffective in the treatment of chronic nonfluent aphasia
Abstract
The effect of bromocriptine on chronic nonfluent aphasia was investigated in 4 patients suffering from a stroke 24 to 35 months before the onset of this study (average 29 months). Two patients had Broca, one had global and the other transcortical motor aphasia. CT-scans demonstrated anterior-posterior infarctions in 3 patients and anterior infarction in one. Bromocriptine was given initially at a dosage of 10 mg/day, and of 25 mg/day during the follow ups. By means of aphasia tests, bromocriptine was found to be ineffective for the treatment of any symptoms of chronic nonfluent aphasia.
Similar articles
-
A randomized, double-blind trial of bromocriptine efficacy in nonfluent aphasia after stroke.Neurology. 2006 Mar 28;66(6):914-6. doi: 10.1212/01.wnl.0000203119.91762.0c. Neurology. 2006. PMID: 16567711 Clinical Trial.
-
An open-label trial of bromocriptine in nonfluent aphasia: a qualitative analysis of word storage and retrieval.Brain Lang. 2000 Sep;74(2):141-56. doi: 10.1006/brln.2000.2332. Brain Lang. 2000. PMID: 10950911 Clinical Trial.
-
Bromocriptine treatment of nonfluent aphasia.Neurology. 1995 Dec;45(12):2170-3. doi: 10.1212/wnl.45.12.2170. Neurology. 1995. PMID: 8848187 Clinical Trial.
-
Drug treatment of poststroke aphasia.Expert Rev Neurother. 2004 Mar;4(2):211-7. doi: 10.1586/14737175.4.2.211. Expert Rev Neurother. 2004. PMID: 15853562 Review.
-
Clinical, neuroimaging, and pathologic features of progressive nonfluent aphasia.Ann Neurol. 1996 Feb;39(2):166-73. doi: 10.1002/ana.410390205. Ann Neurol. 1996. PMID: 8967747 Review.
Cited by
-
Drug therapy of post-stroke aphasia: a review of current evidence.Neuropsychol Rev. 2011 Sep;21(3):302-17. doi: 10.1007/s11065-011-9177-7. Epub 2011 Aug 16. Neuropsychol Rev. 2011. PMID: 21845354 Review.
-
Pharmacological treatment for aphasia following stroke.Cochrane Database Syst Rev. 2001;2001(4):CD000424. doi: 10.1002/14651858.CD000424. Cochrane Database Syst Rev. 2001. PMID: 11687079 Free PMC article.
-
Neuroscience insights improve neurorehabilitation of poststroke aphasia.Nat Rev Neurol. 2011 Feb;7(2):86-97. doi: 10.1038/nrneurol.2010.201. Nat Rev Neurol. 2011. PMID: 21297651 Review.
-
Psycholinguistics of Aphasia Pharmacotherapy: Asking the Right Questions.Aphasiology. 2014 Jan 1;28(2):133-154. doi: 10.1080/02687038.2013.818099. Aphasiology. 2014. PMID: 24489425 Free PMC article.
-
Dopaminergic therapy in aphasia.Aphasiology. 2012 Feb;28(2):155-170. doi: 10.1080/02687038.2013.802286. Aphasiology. 2012. PMID: 25076804 Free PMC article. Review.