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. 1995 Dec 15;312 ( Pt 3)(Pt 3):713-6.
doi: 10.1042/bj3120713.

Identification of polymorphism at the glutathione S-transferase, GSTM3 locus: evidence for linkage with GSTM1*A

A Inskip  1 , J Elexperu-Camiruaga, N Buxton, P S Dias, J MacIntosh, D Campbell, P W Jones, L Yengi, J A Talbot, R C Strange, et al.
Affiliations

Identification of polymorphism at the glutathione S-transferase, GSTM3 locus: evidence for linkage with GSTM1*A

A Inskip et al. Biochem J. .

Abstract

Allelism in the glutathione S-transferase, GSTM3 gene has been identified using PCR with specific primers to exon 6/exon 7. Sequencing showed the mutant GSTM3*B allele to have a three-base deletion in intron 6 with a frequency of 0.158. The mutation generates a recognition sequence, 5'-AAGATA-3', for the negative transcription factor YY1. GSTM3*B was significantly associated with GSTM1*A.

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References

    1. Carcinogenesis. 1995 Apr;16(4):707-11 - PubMed
    1. J Biochem. 1994 Aug;116(2):321-6 - PubMed
    1. Cell. 1982 Jun;29(2):319-28 - PubMed
    1. Ann Hum Genet. 1987 May;51(Pt 2):95-106 - PubMed
    1. J Biol Chem. 1990 Jun 5;265(16):9188-93 - PubMed

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