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Comparative Study
. 1994 Jul;1(4):401-5.
doi: 10.1128/cdli.1.4.401-405.1994.

The Vitek immunodiagnostic assay for detection of immunoglobulin M toxoplasma antibodies

E Candolfi  1 , R Ramirez, M P Hadju, C Shubert, J S Remington
Affiliations
Comparative Study

The Vitek immunodiagnostic assay for detection of immunoglobulin M toxoplasma antibodies

E Candolfi et al. Clin Diagn Lab Immunol. 1994 Jul.

Abstract

We compared the Vitek immunodiagnostic assay for detection of immunoglobulin M (IgM) toxoplasma antibodies (VIDAS TXM) with an IgM enzyme-linked immunosorbent assay (ELISA) which we developed. A total of 407 serum samples from 391 adults were used for this study. We also examined 17 serial serum samples from four women who had seroconverted during gestation. We observed a sensitivity of 99.5%, a specificity of 93%, a positive predictive value of 93.6%, a negative predictive value of 99.5%, and a global agreement of 96.3%. In each case of seroconversion the VIDAS TXM became positive at the same time as did the IgM ELISA.

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