Mazindol treatment for cocaine dependence
- PMID: 8556974
- DOI: 10.1016/0376-8716(95)01174-4
Mazindol treatment for cocaine dependence
Abstract
This double-blind placebo-controlled treatment study tested the efficacy of mazindol in currently cocaine-dependent out-patients. Forty-three patients were randomized to mazindol (2 mg QD) vs. placebo treatment for 6 weeks. All patients received weekly group counseling. Patients improved with respect to objective (urine toxicology) and subjective (self-report of times used, dollars spent, craving, etc.) measures. There was no response difference between patients treated with mazindol and those who received placebo.
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