Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Jan;64(1):355-7.
doi: 10.1128/iai.64.1.355-357.1996.

Protective immunity to Shiga-like toxin I following oral immunization with Shiga-like toxin I B-subunit-producing Vibrio cholerae CVD 103-HgR

D W Acheson  1 , M M Levine, J B Kaper, G T Keusch
Affiliations

Protective immunity to Shiga-like toxin I following oral immunization with Shiga-like toxin I B-subunit-producing Vibrio cholerae CVD 103-HgR

D W Acheson et al. Infect Immun. 1996 Jan.

Abstract

This study addresses a mechanism for inducing systemic immunity to Shiga-like toxins by oral administration of a Shiga-like toxin I B-subunit-expressing Vibrio cholerae vaccine strain [CVD 103-HgR(pDA60)]. Two sets of three rabbits were given either CVD 103-HgR or CVD 103-HgR(pDA60) orally. All rabbits immunized with CVD 103-HgR(pDA60) developed neutralizing serum antibodies to Shiga-like toxin I. None of the controls developed such antibodies.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Clin Microbiol. 1980 Sep;12(3):361-6 - PubMed
    1. Infect Immun. 1995 Jan;63(1):301-8 - PubMed
    1. J Exp Med. 1986 Jun 1;163(6):1391-404 - PubMed
    1. Am J Clin Pathol. 1986 Jul;86(1):108-12 - PubMed
    1. Eur J Biochem. 1988 Jan 15;171(1-2):45-50 - PubMed

Publication types