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. 1977 Mar 25;486(3):579-82.
doi: 10.1016/0005-2760(77)90112-6.

Distribution of prostaglandin biosynthetic pathways in several rat tissues. Formation of 6-ketoprostaglandin F1alpha

C R Pace-Asciak, G Rangaraj

Distribution of prostaglandin biosynthetic pathways in several rat tissues. Formation of 6-ketoprostaglandin F1alpha

C R Pace-Asciak et al. Biochim Biophys Acta. .

Abstract

The capacity of homogenates of rat lung, liver, spleen, whole stomach, stomach fundus, kidney and heart to form prostaglandin E2, F2alpha, D2, thromboxane B2 and 6-ketoprostaglandin F1alpha was investigated. All products were quantitated by mass spectrometry. The results demonstrated interesting differences between tissues in the direction of the 'prostaglandin synthetase' to specific products (e.g. as in spleen and stomach).

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