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. 1995 Jul-Aug;25(4):307-10.
doi: 10.1007/BF02360042.

Influence of emotional-algic stress on the activity of carboxypeptidase H--an enzyme involved in processing rat brain neuropeptides

M T Gengin  1 , A N Vernigora
Affiliations

Influence of emotional-algic stress on the activity of carboxypeptidase H--an enzyme involved in processing rat brain neuropeptides

M T Gengin et al. Neurosci Behav Physiol. 1995 Jul-Aug.

Abstract

It was established that the activity of carboxypeptidase H increases in divisions of the brain of rats during a one-time emotional-algic stress. The most substantial increase in the activity of the enzyme is observed in the hypophysis and the hypothalamus. The changes in activity were less marked with chronic emotional-algic stress. The involvement of carboxypeptidase H in the development of stress reactions, as well as the possibility of the participation of the soluble form of the enzyme in the processing of secretory peptides, and of the membrane-bound form in the processing of neuropeptides with a central action, is hypothesized.

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