Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation?
- PMID: 8573169
- DOI: 10.1006/bbrc.1996.0008
Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation?
Abstract
In this article we demonstrate the immunocytochemical localization of nitric oxide synthase in mitochondria isolated from heart, skeletal muscle, and kidney, using a monoclonal antibody directed against the endothelial form of nitric oxide synthase. The possibility that mitochondrially located nitric oxide synthase is a ubiquitous regulator of mitochondrial oxidative phosphorylation in mammalian cells is discussed.
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