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Review
. 1995 Oct;17(4 Suppl):353S-364S.
doi: 10.1016/8756-3282(95)00313-3.

Perspectives of pQCT technology associated to biomechanical studies in skeletal research employing rat models

J L Ferretti  1
Affiliations
Review

Perspectives of pQCT technology associated to biomechanical studies in skeletal research employing rat models

J L Ferretti. Bone. 1995 Oct.

Abstract

Assessment of bone material quality and architectural indicators by means of peripheral quantitative computed tomography (pQCT) offers a wide perspective for skeletal research employing noninvasive procedures. Some mechanically-validated examples of these pQCT applications in animal models are described. They concern (a) the analysis of bone mechanostatical interrelationships as shown by experimental "distribution/quality" curves, and (b) the noninvasive determination of bone strength. An attractive attempt to extrapolate the latter to human bone studies is also discussed.

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