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Case Reports
. 1995 Jun;18(1-2):189-93.
doi: 10.3109/10428199509064942.

Differentiation of extramedullary acute promyelocytic leukemia by all-trans-retinoic acid

C A Lederman  1 , J Weisberger, K Seiter, E J Feldman
Affiliations
Case Reports

Differentiation of extramedullary acute promyelocytic leukemia by all-trans-retinoic acid

C A Lederman et al. Leuk Lymphoma. 1995 Jun.

Abstract

The effect of all-trans-retinoic acid (ATRA) on extramedullary acute promyelocytic leukemia (APL) has not been fully delineated. We report an unusual case of APL in which a patient relapsed in the skin and central nervous system. Cytodifferentiation of leukemic cells from these extramedullary sites was demonstrated following treatment with ATRA.

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