Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Apr 26;125(1):71-80.
doi: 10.1007/BF00470607.

Neonatal hypophosphatasia with elevated serum parathyroid hormone

H Maesaka, N Niitsu, S Suwa, T Fujita

Neonatal hypophosphatasia with elevated serum parathyroid hormone

H Maesaka et al. Eur J Pediatr. .

Abstract

Two cases of neonatal hypophosphatasia are described. In case 1, hypercalcemia developed at 2 1/2 months of age and continued until death at 10 1/2 months of age. Serum calcium levels decreased transiently in response to phosphate supplementation, prednisolone, and calcitonin. Significantly elevated levels of PTH were detected at 2 1/2 months of age. At autopsy, no parathyroid glands were found. In case 2, hypercalcemia was not detected in his course. Elevated level of serum PTH was recorded on the 17th day of life. A post-mortem examination revealed the presence of one normal parathyroid gland.

PubMed Disclaimer

References

    1. Ann Intern Med. 1966 Oct;65(4):722-9 - PubMed
    1. Am J Med. 1973 Nov;55(5):577-81 - PubMed
    1. Lancet. 1956 Apr 28;270(6922):553 - PubMed
    1. Metabolism. 1974 Oct;23(10):975-1007 - PubMed
    1. Am J Med Sci. 1968 Mar;255 :163-70 - PubMed