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Review
. 1995:384:323-38.
doi: 10.1007/978-1-4899-1016-5_26.

The significance of motor unit variability in sustaining mechanical output of muscle

Affiliations
Review

The significance of motor unit variability in sustaining mechanical output of muscle

A J Sargeant et al. Adv Exp Med Biol. 1995.

Abstract

Neuromuscular function and fatigue have been studied using a wide variety of preparations. These range from sections of single fibers from which the cell membrane has been removed to whole muscles or groups of muscles acting about a joint in the intact animal. Each type of preparation has its merits and limitations. There is no ideal preparation; rather the question to be answered will determine the most appropriate model in each case and sometimes a combination of approaches will be needed. In particular, it is important to understand how the mechanical output of whole muscle can be sustained to meet the demands of a task and to take into account the organized variability of the constituent motor units.

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