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. 1995 Nov-Dec;16(10):2001-7.

MR anatomy of the substantia innominata and findings in Alzheimer disease: a preliminary report

M Sasaki  1 , S Ehara, Y Tamakawa, S Takahashi, H Tohgi, A Sakai, T Mita
Affiliations

MR anatomy of the substantia innominata and findings in Alzheimer disease: a preliminary report

M Sasaki et al. AJNR Am J Neuroradiol. 1995 Nov-Dec.

Abstract

Purpose: To demonstrate normal MR anatomy of the substantia innominata and its changes in Alzheimer disease on MR imaging.

Methods: Using a 1.5-T superconductive MR unit, thickness of the substantia innominata was measured on coronal thin-section images obtained in 22 patients with Alzheimer disease and 14 age-matched control subjects. Comparison of these images with postmortem specimens of human brain was also performed.

Results: On T2-weighted images through the anterior commissure, the substantia innominata was clearly identified between the globus pallidus and the anterior perforated substance. In Alzheimer disease, thinning of the substantia innominata was more frequently observed than in the age-matched controls.

Conclusion: Thin-section T2-weighted coronal MR images can demonstrate shrinkage of the substantia innominata, a finding that may aid in the diagnosis of Alzheimer disease.

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  • Where's the chicken?
    Huckman MS. Huckman MS. AJNR Am J Neuroradiol. 1995 Nov-Dec;16(10):2008-9. AJNR Am J Neuroradiol. 1995. PMID: 8585487 Free PMC article. No abstract available.

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