doi: 10.1210/jcem-44-5-983.
The binding of a synthetic progestin, R5020 to transcortin and serum albumin
- PMID: 858781
- DOI: 10.1210/jcem-44-5-983
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The binding of a synthetic progestin, R5020 to transcortin and serum albumin
J Clin Endocrinol Metab.
1977 May.
Abstract
R5020 (17,21-dimethyl-19-nor-4,9-pregnadiene-3,20-dione), a synthetic progestin, was tested for its binding to purified human transcortin, albumin and human serum. Scatchard analysis showed that R5020 bound relatively weakly to transcortin (Kass = 8 X 10(6)M-1); in 20% human serum or albumin greater than 90% was bound with low Kass and an indeterminate number of binding sites.
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