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Review
. 1995 Dec;6(12):1619-40.
doi: 10.1091/mbc.6.12.1619.

Force generation by microtubule assembly/disassembly in mitosis and related movements

S Inoué  1 , E D Salmon
Affiliations
Free PMC article
Review

Force generation by microtubule assembly/disassembly in mitosis and related movements

S Inoué et al. Mol Biol Cell. 1995 Dec.
Free PMC article

Abstract

In this article, we review the dynamic nature of the filaments (microtubules) that make up the labile fibers of the mitotic spindle and asters, we discuss the roles that assembly and disassembly of microtubules play in mitosis, and we consider how such assembling and disassembling polymer filaments can generate forces that are utilized by the living cell in mitosis and related movements.

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