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Comparative Study
. 1977 Apr 1;55(7):355-6.
doi: 10.1007/BF01488117.

[Digoxin and beta-methyldigoxin concentrations in cerebrospinal fluid and plasma (author's transl)]

[Article in German]
G Bodem, U Boldt, H Ochs
Comparative Study

[Digoxin and beta-methyldigoxin concentrations in cerebrospinal fluid and plasma (author's transl)]

[Article in German]
G Bodem et al. Klin Wochenschr. .

Abstract

12 patients were treated for at least two days with digoxin or beta-methyldigoxin before a lumbar punction was done for diagnostic purposes. At the same time venous blood was drawn and both samples were radioimmunologically analysed for digoxin concentration. The relationship of concentrations from plasma to cerebrospinal fluid was 2 for beta-methyldigoxin and 8 for digoxin.

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References

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    1. Naunyn Schmiedebergs Arch Pharmacol. 1974;286(2):195-210 - PubMed
    1. J Clin Invest. 1974 Dec;54(6):1365-72 - PubMed