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. 1995 Nov;58(11):1655-61.
doi: 10.1021/np50125a002.

New steroid acids from Antrodia cinnamomea, a fungal parasite of Cinnamomum micranthum

C H Chen  1 , S W Yang, Y C Shen
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New steroid acids from Antrodia cinnamomea, a fungal parasite of Cinnamomum micranthum

C H Chen et al. J Nat Prod. 1995 Nov.

Abstract

Three new steroids, zhankuic acids A [1], B [2], and C [3], were isolated from the fruiting bodies of Antrodia cinnamomea by bioassay-guided fractionation. The structures of these compounds were elucidated by chemical reactions and detailed analysis of their 1H- and 13C-nmr spectra. Biological studies revealed that 1 exhibited cytotoxic activity against P-388 murine leukemia cells and 2 showed weak anticholinergic and antiserotonergic activities.

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