New steroid acids from Antrodia cinnamomea, a fungal parasite of Cinnamomum micranthum
- PMID: 8594142
- DOI: 10.1021/np50125a002
New steroid acids from Antrodia cinnamomea, a fungal parasite of Cinnamomum micranthum
Abstract
Three new steroids, zhankuic acids A [1], B [2], and C [3], were isolated from the fruiting bodies of Antrodia cinnamomea by bioassay-guided fractionation. The structures of these compounds were elucidated by chemical reactions and detailed analysis of their 1H- and 13C-nmr spectra. Biological studies revealed that 1 exhibited cytotoxic activity against P-388 murine leukemia cells and 2 showed weak anticholinergic and antiserotonergic activities.
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