[Iron oxides as contrast agents for MRI of the liver]

Abstract

Iron oxide particles are a potent class of MR contrast agents. Depending on their size and formulation, iron oxides are selectively taken up by the reticuloendothelial system or the hepatocytes. Experimental and clinical studies have shown that iron oxides can improve the detection and the characterization of liver tumors and can contribute to the detection of diffuse liver lesions. These tissue-specific MR contrast agents combine anatomic and functional information about liver lesions.