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Review
. 1995 Oct;73(5):414-7.
doi: 10.1038/icb.1995.64.

Acute on chronic bronchitis: A model of mucosal immunology

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Review

Acute on chronic bronchitis: A model of mucosal immunology

R Clancy et al. Immunol Cell Biol. 1995 Oct.

Abstract

Acute bronchitis has been studied as a model of disturbed mucosal immunoregulation. A new hypothesis relating to the pathogenesis of acute bronchitis has been developed, based on altered host response as the prime mover. Infection-prone subjects had low levels of lysozyme. Effective oral immunization, especially if early, reduced levels of bacterial colonization. Future attention focuses on intra bronchial inflammation and its link to the host-parasite relationship.

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