Mortality in systemic sclerosis: a comparison with the general population
- PMID: 8596151
Mortality in systemic sclerosis: a comparison with the general population
Abstract
Objective: To compare the mortality rate in patients with systemic sclerosis (SSc) with that of the general population.
Methods: Standardized mortality ratios (SMR) were calculated for 237 patients with SSc followed prospectively, using age and sex specific mortality rates in Ontario for the period 1976-1990.
Results: The overall SMR for the SSc cohort was 4.69. The mortality rate was greater with diffuse than with limited scleroderma (SMR 6.18 and 3.80, respectively), but not different between men and women.
Conclusion: The mortality rate in SSc is increased compared to that of the general population, especially in the subset with diffuse disease.
Similar articles
-
Epidemiology and mortality of systemic sclerosis: a nationwide population study in Taiwan.Scand J Rheumatol. 2011;40(5):373-8. doi: 10.3109/03009742.2011.553736. Epub 2011 Mar 9. Scand J Rheumatol. 2011. PMID: 21388247
-
Influence of clinical features, serum antinuclear antibodies, and lung function on survival of patients with systemic sclerosis.J Rheumatol. 2001 Nov;28(11):2454-9. J Rheumatol. 2001. PMID: 11708418
-
Increased prevalence of scleroderma in southwestern Ontario: a cluster analysis.J Rheumatol. 2002 Sep;29(9):1867-73. J Rheumatol. 2002. PMID: 12233880
-
Mortality in systemic sclerosis: lessons learned from population-based and observational cohort studies.Curr Opin Rheumatol. 2014 Mar;26(2):131-7. doi: 10.1097/BOR.0000000000000027. Curr Opin Rheumatol. 2014. PMID: 24441644 Review.
-
Determinants of mortality in systemic sclerosis: a focused review.Rheumatol Int. 2018 Oct;38(10):1847-1858. doi: 10.1007/s00296-017-3826-y. Epub 2017 Nov 7. Rheumatol Int. 2018. PMID: 29116439 Review.
Cited by
-
Clinical features and prognosis of primary biliary cirrhosis associated with systemic sclerosis.Gut. 2006 Mar;55(3):388-94. doi: 10.1136/gut.2005.075002. Epub 2005 Sep 8. Gut. 2006. PMID: 16150855 Free PMC article.
-
Standardized mortality ratios in systemic sclerosis: a meta-analysis assessing overall and sex- and disease subtype-specific differences.Z Rheumatol. 2024 Feb;83(Suppl 1):175-182. doi: 10.1007/s00393-023-01401-x. Epub 2023 Aug 19. Z Rheumatol. 2024. PMID: 37597012 English.
-
Primary biliary cirrhosis associated with systemic sclerosis: diagnostic and clinical challenges.Int J Rheumatol. 2011;2011:976427. doi: 10.1155/2011/976427. Epub 2011 Dec 6. Int J Rheumatol. 2011. PMID: 22187566 Free PMC article.
-
Overall and sex- and disease subtype-specific mortality in patients with systemic sclerosis : An updated meta-analysis.Z Rheumatol. 2019 Mar;78(2):195-201. doi: 10.1007/s00393-018-0492-8. Z Rheumatol. 2019. PMID: 29869154 English.
-
Hematopoietic stem cell transplantation for auto immune rheumatic diseases.World J Transplant. 2016 Mar 24;6(1):199-205. doi: 10.5500/wjt.v6.i1.199. World J Transplant. 2016. PMID: 27011918 Free PMC article. Review.