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. 1996 Apr;64(4):1480-3.
doi: 10.1128/iai.64.4.1480-1483.1996.

CD36 and intercellular adhesion molecule 1 mediate adhesion of developing Plasmodium falciparum gametocytes

N J Rogers  1 , O Daramola, G A Targett, B S Hall
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CD36 and intercellular adhesion molecule 1 mediate adhesion of developing Plasmodium falciparum gametocytes

N J Rogers et al. Infect Immun. 1996 Apr.

Abstract

Plasmodium falciparum trophozoite-infected erythrocytes adhere to the amelanotic melanoma C32 cell line in vitro. Here we demonstrate for the first time that immature gametocyte-infected erythrocytes also adhere to C32 cells, albeit at lower levels than trophozoites. However, anti-CD36 and anti-intercellular adhesion molecule 1 antibodies inhibit asexual and gametocyte adhesion by comparable percentages, suggesting a common dependency for binding to these cellular receptors.

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