Primary sequence and evolutionary conservation of ribosomal protein genes from the domestic cat

Abstract

Ribosomal proteins complex with ribosomal RNA to form the subunits of the ribosome, and as such, serve essential functions in protein synthesis. Accumulating evidence suggests that ribosomal proteins are bifunctional molecules with roles in diverse cellular processes in addition to protein synthesis. Previous studies have demonstrated that expression of four ribosomal proteins. L41, S3a, S4, and S17, is elevated in malignant lymphomas of the domestic cat. Reported here is the nucleotide sequence of cDNA clones encoding feline ribosomal proteins L41, S3a, S4, and S17.