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. 1996 Mar 1;1315(2):73-7.
doi: 10.1016/0925-4439(95)00118-2.

Modification of the extracellular matrix following myocardial infarction monitored by FTIR spectroscopy

K Lui  1 , M Jackson, M G Sowa, H Ju, I M Dixon, H H Mantsch
Affiliations
Free article

Modification of the extracellular matrix following myocardial infarction monitored by FTIR spectroscopy

K Lui et al. Biochim Biophys Acta. .
Free article

Abstract

Comparison of mid- and near-infrared spectra of control and infarcted rat ventricular tissue reveals the presence of absorptions in infarcted tissue which are highly characteristics of collagen, indicating large scale deposition of type I collagen in the myocardium following infarction. These results demonstrate that IR spectroscopy may be used to rapidly monitor the modifications of the extracellular matrix associated with myocardial infarction.

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