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. 1977 Mar-Jun;72(2-3):247-53.
doi: 10.1007/BF01906369.

Transformation of morphological, functional and metabolic properties of fast-twitch muscle as induced by long-term electrical stimulation

D Pette, C Heilmann

Transformation of morphological, functional and metabolic properties of fast-twitch muscle as induced by long-term electrical stimulation

D Pette et al. Basic Res Cardiol. 1977 Mar-Jun.

Abstract

Transformation of structural, functional, metabolic and molecular characteristics is induced by stimulating fast-twitch muscles with the frequency pattern of a motoneuron normally innervating a slow-twitch muscle. These changes correspond to a transition of a "fast-white" into a "slow-red" muscle. Intermittent stimulation (8 h/d) does not affect the system but causes alterations of the sarcoplasmic reticulum which lead to changes in time to peak and half relaxation time. Continuous stimulation (24 h/d) induces a transformation of the muscle also at the level of the myosin system.

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References

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