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Case Reports
. 1996 May;37(5):501-2.
doi: 10.1111/j.1528-1157.1996.tb00598.x.

Gabapentin associated with aggressive behavior in pediatric patients with seizures

K B Tallian  1 , M C Nahata, W Lo, C Y Tsao
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Case Reports

Gabapentin associated with aggressive behavior in pediatric patients with seizures

K B Tallian et al. Epilepsia. 1996 May.

Abstract

Gabapentin (GBP) is a new antiepileptic drug (AED) approved for adjunctive treatment of complex partial seizures with or without seizures secondarily generalization in adults. We report 2 children who received GBP for intractable seizures and who developed intolerable aggressive behavior requiring dose reduction or drug discontinuation. Behavioral changes should be recognized as a possible side effect of GBP, especially in mentally retarded children.

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