Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Apr 15;52(4):353-6.
doi: 10.1007/BF01919540.

The action of the cholecystokinin-A receptor antagonist, devazepide, on the digestive system of the chicken

M Furuse  1 , Y H Choi, S Satoh, J Okumura
Affiliations

The action of the cholecystokinin-A receptor antagonist, devazepide, on the digestive system of the chicken

M Furuse et al. Experientia. .

Abstract

The influence of the cholecystokinin (CCK)-A receptor antagonist, devazepide (DVZ), on the chicken digestive tract was investigated. The passage of food from the crops of birds treated with DVZ was not significantly different from that of the control. DVZ treatment did not inhibit the biliary flow stimulated by the CCK analogue, caerulein. Dispersed chicken pancreatic acini stimulated with CCK were treated with various concentrations of DVZ. At 10-5 M, DVZ completely inhibited amylase release; this concentration was much higher than those reported to have similar effects in mammals. The results suggest that the action DVZ as a CCK antagonist in the chicken is very weak.

PubMed Disclaimer

References

    1. FEBS Lett. 1986 Sep 15;205(2):318-22 - PubMed
    1. Pancreas. 1988;3(1):95-8 - PubMed
    1. Experientia. 1994 Sep 15;50(9):812-4 - PubMed
    1. Nature. 1993 Mar 25;362(6418):348-50 - PubMed
    1. Science. 1990 Mar 30;247(4950):1589-91 - PubMed

Publication types