Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1996 Apr 15;24(8):1428-34.
doi: 10.1093/nar/24.8.1428.

Afut1, a retrotransposon-like element from Aspergillus fumigatus

C Neuveglise  1 , J Sarfati, J P Latge, S Paris
Affiliations

Afut1, a retrotransposon-like element from Aspergillus fumigatus

C Neuveglise et al. Nucleic Acids Res. .

Abstract

A repeated DNA sequence used for epidemiological studies of the human opportunistic pathogen Aspergillus fumigatus has been characterized. It is a retroelement of 6914 bp in length, bounded by long terminal repeats of 282 bp, with sequence and features characteristic of retroviruses and retrotransposons. A 5 bp duplication site was found at its borders. This element, designated Afut1, encodes amino acid sequences homologous to the reverse transcriptase, RNase H and endonuclease encoded by the pol genes of retroelements. Comparison of the peptidic sequences with other putative polypeptides of fungal LTR retrotransposons showed that Afut1 is a member of the gypsy group. This is the first report of a transposable element in A.fumigatus. Afut1 is a defective element: the putative coding domains contain multiple stop codons due exclusively to transitions from C:G to T:A.

PubMed Disclaimer

References

    1. Mol Biol Evol. 1993 Nov;10(6):1370-9 - PubMed
    1. J Clin Microbiol. 1993 Jun;31(6):1547-54 - PubMed
    1. J Bacteriol. 1994 May;176(9):2477-82 - PubMed
    1. J Clin Microbiol. 1994 Mar;32(3):684-90 - PubMed
    1. Appl Environ Microbiol. 1995 Jan;61(1):103-8 - PubMed

Publication types

Associated data