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. 1977 May;32(5):315-23.

Interaction of new derivatives of daunorubicin and adriamycin with DNA

  • PMID: 862886

Interaction of new derivatives of daunorubicin and adriamycin with DNA

E Arlandini et al. Farmaco Sci. 1977 May.

Abstract

The interaction of a number of new derivatives of the antitumour antibiotics daunorubicin and adriamycin with calf-thymus DNA has been studied by equilibrium dialysis and low-shear viscosimetry. The results are interpreted in terms of structure of the compounds, also by examining molecular stereomodels.

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