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Comparative Study
. 1996 May 6;222(1):178-80.
doi: 10.1006/bbrc.1996.0717.

Cloning and expression of human homolog HSMT3 to yeast SMT3 suppressor of MIF2 mutations in a centromere protein gene

H Mannen  1 , H M Tseng, C L Cho, S S Li
Affiliations
Comparative Study

Cloning and expression of human homolog HSMT3 to yeast SMT3 suppressor of MIF2 mutations in a centromere protein gene

H Mannen et al. Biochem Biophys Res Commun. .

Abstract

A human HSMT3 cDNA encoding a homolog of the yeast SMT3, a suppressor of MIF2 mutations in a centromere protein gene, was identified and sequenced. The sequence of 95 amino acids deduced from the human HSMT3 cDNA exhibited 51.1% identity and 69.6% similarity to the yeast Smt3p sequence. The HSMT3 transcripts of 1.35Kb were found to be abundantly expressed in various human tissues.

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