doi: 10.1083/jcb.133.3.507.
A v-SNARE implicated in intra-Golgi transport
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- PMID: 8636227
- PMCID: PMC2120813
- DOI: 10.1083/jcb.133.3.507
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A v-SNARE implicated in intra-Golgi transport
J Cell Biol.
1996 May.
Abstract
We report the identification of a putative v-SNARE (GOS-28), localized primarily to transport vesicles at the terminal rims of Golgi stacks. In vitro, GOS-28, A Golgi SNARE of 28 kD, is efficiently packaged into Golgi-derived vesicles, which are most likely COPI coated. Antibodies directed against GOS-28 block its ability to bind alpha-SNAP, partially inhibit transport from the cis to the medial cisternae, and do not inhibit budding of COP-coated vesicles, but do accumulate docked uncoated vesicles.
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