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Case Reports
. 1996 Feb;128(2):241-3.
doi: 10.1016/s0022-3476(96)70398-0.

Persistence of fetal hemoglobin production after successful transplantation of cord blood stem cells in a patient with sickle cell anemia

B Brichard  1 , C Vermylen, J Ninane, G Cornu
Affiliations
Case Reports

Persistence of fetal hemoglobin production after successful transplantation of cord blood stem cells in a patient with sickle cell anemia

B Brichard et al. J Pediatr. 1996 Feb.

Abstract

A girl with sickle cell anemia was treated with cord blood transplantation combined with hematopoietic growth factor. Cord blood cells were collected from a sister with an identical human leukocyte antigen complex who was a carrier of the sickle cell trait (hemoglobin AS). The patient had complete engraftment and no graft-versus-host disease. The persistence of a high level of fetal hemoglobin 6 months after engraftment was noted.

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