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. 1996 Mar;64(3):1016-9.
doi: 10.1128/iai.64.3.1016-1019.1996.

Translocation of Yersinia enterocolitica through an endothelial monolayer by polymorphonuclear leukocytes

H Rüssmann  1 , K Ruckdeschel, J Heesemann
Affiliations

Translocation of Yersinia enterocolitica through an endothelial monolayer by polymorphonuclear leukocytes

H Rüssmann et al. Infect Immun. 1996 Mar.

Abstract

An endothelial cell monolayer grown on a microporous membrane coated with basement membrane protein matrix was used to study translocation of yersinia-infected human polymorphonuclear leukocytes (PMNs). PMNs infected with one to eight bacteria were able to translocate living yersiniae from the upper chamber to the chemoattractant-containing lower chamber. This process may contribute to extravasation and dissemination of yersiniae in the infected host.

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