Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1996 May-Jun;46(3):142-64.
doi: 10.3322/canjclin.46.3.142.

The use of bone marrow and peripheral blood stem cell transplantation in the treatment of cancer

F R Appelbaum  1
Affiliations
Free article
Review

The use of bone marrow and peripheral blood stem cell transplantation in the treatment of cancer

F R Appelbaum. CA Cancer J Clin. 1996 May-Jun.
Free article

Abstract

Since its first successful application 25 years ago, the clinical use of bone marrow and peripheral blood stem cell transplantation has increased dramatically. Transplantation allows for the administration of high doses of systematic chemotherapy and radiotherapy and confers an antitumor effect separate from the effects of chemotherapy. However,complications including toxicity of treatment, graft failure, and graft-versus-host disease exist. This article reviews the history and current use of bone marrow and peripheral blood stem cell transplantation and outlines new approaches for clinical application.

PubMed Disclaimer

Comment in

  • Cancer therapy--the 21st century.
    Rosenthal DS. Rosenthal DS. CA Cancer J Clin. 1996 May-Jun;46(3):131-3. doi: 10.3322/canjclin.46.3.131. CA Cancer J Clin. 1996. PMID: 8646543

Publication types

MeSH terms

LinkOut - more resources